See Paper Integrity in Action

The infamous 1998 paper that sparked the anti-vaccine movement. Fully retracted for fraud, data fabrication, and ethical violations. Shows how Paper Integrity catches retracted papers.

Highly influential psychology paper (7,000+ citations) whose findings failed to replicate in large pre-registered studies. A cautionary tale of small-sample research.

Landmark pharma trial that downplayed cardiovascular risks. NEJM issued an Expression of Concern. Vioxx was later withdrawn after causing ~100,000 heart attacks.

Famous 'power pose' study claiming 2-minute poses change hormones. Lead author has publicly disavowed it. Hormonal findings failed to replicate.

Fraudulent COVID-19 study claiming hydroxychloroquine harm. Data came from a company whose database likely never existed. Retracted within 2 weeks.

Exemplary COVID-19 trial showing dexamethasone saves lives. Large, pre-registered, independent, transparent. This is what high-quality evidence looks like.

Foundational 1999 Nature Cell Biology paper on integrin-cytoskeleton interactions. 259 citations, clean record. Shows how Paper Integrity handles legitimate, well-conducted research.

Groundbreaking NEJM trial demonstrating CRISPR gene editing as a functional cure for sickle cell disease. High methodological rigor with novel therapeutic approach.

SUSTAIN-6 trial published in NEJM showing cardiovascular benefits of semaglutide. Industry-funded but well-designed with pre-registration.

Randomized clinical trial in JAMA Psychiatry testing psilocybin for depression. Small sample size but rigorous design with waitlist control.

DeepMind's AlphaFold2 paper in Nature — revolutionized structural biology. Computational study with extensive validation against experimental structures.

Science paper linking gut bacteria to cancer immunotherapy response. Observational with small cohort but significant clinical implications.